Ribosome-inactivating Proteins: Ricin and Related Proteins
Fiorenzo Stirpe, Douglas A. Lappi
This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain.
Rok:
2014
Wydawnictwo:
Wiley-Blackwell
Język:
english
ISBN 10:
1118125657
ISBN 13:
9781118125656
Plik:
PDF, 7.38 MB
IPFS:
,
english, 2014
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